Pure 5-MeO DMT Crystal

5-MeO-DMT is a psychedelic alkaloid of the tryptamine class, four to six times more powerful than its better-known relative, N,N-dimethyltryptamine. Interestingly, 5-MeO-DMT actually contains N,N-DMT, and is simply a methoxylated N,N-DMT molecule.

5-MeO-DMT is most commonly found in the milky white venom of the Sonoran Desert Toad (Bufo alvarius/Incilius alvarius), which is native to the southwestern United States and northwestern Mexico. Venom harvesting has put pressure on the population of this ecologically sensitive species, and the species is currently listed as imperiled or locally extinct in several states. 5-MeO-DMT can also be synthetically produced, and out of respect for the endangered Toad species, the 5-MeO-DMT that we offer is synthesized.

5MeoDMT has a long history of ceremonial use among indigenous Amazonians, and the substance has also shown great promise in the treatment of numerous medical conditions. In fact, a single inhalation of the substance has been shown to greatly improve general well-being and mindfulness as well as reduce the symptoms of psychological disorders.

While research into 5-MeO-DMT is limited, a few studies have supported the anecdotal evidence. In a recent preliminary study, 42 participants who took 5-MeO-DMT reported high levels of life satisfaction and mindfulness as well as lower levels of depression and anxiety. These positive effects persisted for up to four weeks (when a follow-up assessment was completed). These results support the findings of a survey of 362 people who had taken 5-MeO-DMT. After using the psychedelic, 80% of respondents reported improvements in anxiety and depression.

5-MeO-DMT has seen a drastic rise in popularity over the past few years as anecdotal reports of its potential as a healing agent have come to light, and as it has been a featured topic in productions including the Joe Rogan Experience, Mike Tyson podcast, and multiple Netflix specials.

The 5-MeO-DMT Experience

Vaporizing or smoking 5-MeO-DMT powder is the most common route of administration. The effects are usually felt within the first 30 seconds after consumption, peaking from 1-15 minutes and lasting for up to half an hour. When taken orally, effects are nonexistent, leading some chemists (most notably Alexander Shulgin) to assume that the act of smoking/vaporizing changes the molecular structure of the compound, making it psychoactive.